Thorowax, Chái Hú, 柴胡, Radix Bupleuri

Disclaimer    For educational purposes only.  Do not use as medical advice

AboutBotanyChinese MedicineCaution
Health Issues
For: Alternating fevers and chills • Cold and flu • Liver Disease • Irregular periods • Organ prolapse

Attributes: Antibiotic • Antipyretic • Anti-inflammatory • Antibaterial • Antiviral • Analgesic • Hepatoprotective • Immunemodulatory • Chemoprotective • Anti-tumor • Cholagogic • Sedative • Immunostimulate

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Dried Herb

Research
Articles:
Constituents: 

Saikosaponins

Photos (Click to enlarge)
Fun Facts
Other Names: Radix BupleuriThorowax Root • Bupleurum Scorzonerifolium • Bupleurum falcatumm • Bupleurum falcatum • Hare's ear root • Saiko • Siho
Plant Family: Apiaceae
Bupleurum is an herb commonly used in Japanese and Chinese medicine for common cold, alternating fever and chills, chronic liver disease, digestive disorders, and malaria.   Saikosaponins is the primary constituent influencing purported benefits.
Species

Bupleurum chinensis (Bei Chai Hu)  - Popularly used for jaundice.  Good for liver diseases and gastric ulcers.

Bupleurum Scorzoneraefolium (Nan Chai Hu)

Bupleurum falcatum

Growth
Bupleurum chinense is NOT in the USDA database. 

USA: Bupleurum chinense is not found in the wild.  

USDA Zones: 3-7

World: 

Habitats: 

Category: Release Exterior Wind Heat 
English: Thorowax      Pinyin:  Chai Hu      Pharmaceutical: Radix Bupleuri  
Organs: Gallbladder • Liver • Pericardium • San Jiao  Temperature: Cool
Taste: Bitter • Pungent  Toxicity:   
Patterns: Deficiency heat • Eye and ear disease • Shao Yang Syndrome (Alternating fevers and chills) • Liver Qi stagnationSpleen Qi sinking • Organ prolapse 
Actions:  Harmonize interior and exterior • Reduce fevers • Reduce chills • Soothe liver Qi • Clear muscle layer heat • Tonify stomach Qi • Guide herbs to Shao Yang Jing
Key 2nd Actions: Guide - PC, LV, GB, UJ, MJ, LJ • Raise Yang Qi • Soothe Liver Qi • Relieve Shao Yang Headache • Treat Hepatitis
Indications: Fever • Chills • Sore throat • Wind heat • Cold/Flu
Contraindications: Dries Yin and can exacerbate the Yin deficiency • Do not use as intramuscular injections • Liver fire • Hyperactive liver yang • Cytochrome P450, 2C9, 2E1, 2D6, and 3A4 • Greater than 19g may lead to liver injury
Typical Dosage: 3g - 9g          Guidelines
Parts Used: Roots          Substitutes:   
Dui Yao: Chai Hu/ Huang Qin - guide to Shao Yang channel, temporal or migraine headache, ear disorders, alternating chills and fever.   
Combine With Purpose
Formulas with Chai Hu
Bu Zhong Yi Qi Tang • Chai Ge Jie Ji Tang •  Chai Hu Jia Long Gu Mu Li Tang • Da Chai Hu Tang • Long Dan Xie Gan TangPu Ji Xiao Du YinRen Shen Bai Du SanSi Ni SanWan Dai TangXiao Chai Hu TangXiao Yao San • Xue Fu Zhu Yu Tang
Herbal Variations of Chai Hu

Alert
  • This herb may interact with drugs related to cytochrome P450 2C9 and can induce CYP2E1, CYP2D6 and CYP3A4 enzymes. (ref)
Potential Drug Interactions

Herbal medicine may interact negatively with pharma drugs and other herbs.  Examples below:

Herbs:

Pharma Drugs:Antibiotics • Interferon • Oflozacin • Tolbutamide • Diabetes medication • Drugs related to cytochrome P450

[3],[5],[8],[17],[18],[21]

Information in this post came from many sources, including class notes, practitioners, websites, webinars, books, magazines, and editor's personal experience.  While the original source often came from historical Chinese texts,  variations may result from the numerous English translations.   Always consult a doctor prior to using these drugs.  The information here is strictly for educational purposes. 

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